Active substance Zonisamide
US Brand Zonegran
IN Brand Zonisep / Zonimid
Manufacturing by SunPharma / Intas
Strength 100mg
Form release Blister 10 capsules
Shipping time 7 – 18 days (Depending from the Country)
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DescriptionDosageSide EffectsPhotos
Zonisamide is used with other medications to prevent and control seizures (epilepsy). Zonisamide is a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor.Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures; infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure.

Table 1. Adults – recommended dosage escalation and maintenance regimen

Treatment Regimen

Titration Phase

Usual Maintenance Dose
Monotherapy – Newly diagnosed adult patients Week 1 + 2 Week 3 + 4 Week 5 + 6  

300 mg per day

(once a day).

If a higher dose is required: increase at two-weekly intervals in increments of 100 mg up to a maximum of 500 mg.

100 mg/day

(once a day)

200 mg /day

(once a day)

300 mg / day

(once a day)

Adjunctive therapy

– with CYP3A4-inducing agents

(see section 4.5)

Week 1 Week 2 Week 3 to 5 300 to 500 mg per day

(once a day or two divided doses).

50 mg/day

(in two divided doses)

100 mg /day

(in two divided doses)

Increase at weekly intervals in increments of 100 mg
– without CYP3A4-inducing agents; or with renal or hepatic impairment Week 1 + 2 Week 3 + 4 Week 5 to 10 300 to 500 mg per day

(once a day or two divided doses).

Some patients may respond to lower doses.

50 mg/day

(in two divided doses)

100 mg / day

(in two divided doses)

Increase at two-weekly intervals in increments of up to 100 mg
Dizziness, drowsiness, trouble sleeping, lack of coordination, lightheadedness, loss of appetite, diarrhea, or double vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.