Active substance | Sorafenib |
US Brand | Nexavar |
IN Brand | Sorafenat, Soranib |
Manufacturing by | Natco, Cipla, India |
Strength | 200mg |
Form release | bottles 120 or 30 tabs |
Estimated shipping time | 7 – 18 days (Depending from the Country) |
Availability, Prices & Order | through request form |
At the current time sorafenib is indicated as a treatment for advanced renal cell carcinoma (RCC), unresectable hepatocellular carcinomas (HCC) and thyroid cancer.
Sorafenib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply.This helps stop the spread of cancer cells.
Treating certain types of kidney, liver or thyroid cancer. It may also be used for other conditions as determined by your doctor.
Sorafenib is a multikinase inhibitor. It works by helping to stop cancer cells from growing.
Usual Adult Dose for Renal Cell Carcinoma
400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.
Usual Adult Dose for Thyroid Cancer
400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.
Usual Adult Dose for Hepatocellular Carcinoma
400 mg twice a day at least one hour before or two hours after eating
Treatment should continue until the patient is no longer clinically benefiting from therapy or until unacceptable toxicity occurs.
In Summary
Commonly reported side effects of sorafenib include: alopecia, arthralgia, desquamation, diarrhea, exfoliation of skin, fatigue, headache, hemorrhage, hypertension, hypophosphatemia, increased serum lipase, lymphocytopenia, neutropenia, palmar-plantar erythrodysesthesia, peripheral sensory neuropathy, pruritus, skin rash, weight loss, increased amylase, and xeroderma. See below for a comprehensive list of adverse effects.