Sertraline (Zoloft)

Active Substance: Sertraline
US Brand: Zoloft
Indian Brand: Sertima / Zosert
Manufacturing: Intas / Sun
Dosage: 100mg
Form release: blister 10 tabs
Shipping time: 9 – 18 days

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Sertraline – selective serotonin reuptake inhibitor antidepressant. Most often based drugs prescribed for this component of obsessive-compulsive disorders. Included in the top four of the new generation of antidepressants according to a study of similar funds in 2009.

Antidepressant, a derivative of naphthylamine. Selective blocker reverse neuronal capture of serotonin in the brain. almost no effect on the neuronal uptake of norepinephrine and dopamine. It does not have a specific affinity for adrenergic and M-holinoretseptorami, of GABA-receptors, dopamine, histamine, serotonin, or benzodiazepine receptors.

Treatment of depressive states of different genesis in patients with mono- and bipolar affective disorder. Prevention of relapse of depression episodes.


Inside – 50 mg 1 time / day, if necessary dose can be increased to 200 mg / day for several weeks.

The effect is manifested through the 7 days after the start of treatment, reaching a maximum after 2-3 weeks.

Side effect

CNS: dizziness, drowsiness, headache, insomnia, fatigue, weakness, tremor; rare – manic or hypomania, anxiety, restlessness, blurred vision.
Since the cardiovascular system: rarely – redness of the skin with a sensation of heat or heat palpitations.
From the digestive system: loss of appetite, diarrhea, dry mouth, nausea, cramps in the stomach or intestines, flatulence; rarely – constipation, vomiting.
On the part of metabolism: increased sweating.
From the reproductive system: rarely – reduced potency.
Allergic reactions: rarely – fever, skin rash, hives, or itching.


Concomitant use with MAO inhibitors, hypersensitivity to sertraline.