|Strength||50mg / 100mg|
|Form release||Blister 10 tabs|
|Shipping time||7 – 18 days (Depending from the Country)|
|Availability & Order||through request form|
Cilostazol is a quinolinone-derivative medication used in the alleviation of the symptoms of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletal.
Although drugs similar to cilostazol have increased the risk of death in patients with congestive heart failure, studies of significant size have not addressed people without the disease.
Cilostazol is a phosphodiesterase inhibitor with therapeutic focus on cyclic adenosine monophosphate (cAMP). It inhibits platelet aggregation and is a direct arterial vasodilator. Its main effects are dilation of the arteries supplying blood to the legs and decreasing platelet coagulation.
Cilostazol is used for:
Reducing symptoms of intermittent claudication (pain, cramping, numbness, or weakness in the legs) that may occur with walking. It may also be used for other conditions as determined by your doctor.
Cilostazol is a phosphodiesterase type 3 inhibitor. Cilostazol works by widening blood vessels to increase blood flow. It also decreases the ability of platelets to stick together and form clots.
Do NOT use cilostazol if:
- you are allergic to any ingredient in cilostazol
- you have heart failure, bleeding problems or a disorder that causes the inability to form blood clots, or active bleeding (eg, bleeding peptic ulcer, bleeding in the brain)
Contact your doctor or health care provider right away if any of these apply to you.
Dosage Forms & Strengths
Peripheral Vascular Disease
100 mg PO q12hr 30 minutes before or 2 hours after meals
- CYP2C19 or CYP3A4 inhibitors: Reduce dosage to 50 mg PO q12hr
Thrombotic Complications of Coronary Angioplasty (Off-label)
100 mg q12hr 30 minutes before or 2 hours after meals
- May be administered alone or in combination with aspirin 81 mg/day
CrCl< 25 mL/min: Use caution
Moderate to severe: Use caution