Tag Archives: AU

Active substance Agomelatine
US Brand Valdoxan
IN Brand Agopose/Noveltin
Manufacturing by Intas / Mankind
Strength 25 mg
Form release blister 10 tablets
Shipping time 7 – 18 days (Depending from the Country)
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DescriptionDosageSide EffectsPhotos

Antidepressants with sleep-promoting effects include sedative antidepressants, for example doxepin, mirtazapine, trazodone, trimipramine, and agomelatine which promotes sleep not through a sedative action but through resynchronization of the circadian rhythm.

Agomelatine is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported not to produce discontinuation syndrome or sexual side effects. Agomelatine may also have positive effects on sleep.
Agomelatine is indicated for the treatment of major depressive episodes in adults. Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder.
Our bodies have a number of important physical and behavioural processes which are controlled by the cycling of day and night. These are called circadian rhythms and, if disrupted, may result in depression. Agomelatine works by helping to restore the balance of these biological rhythms.

ADULT over 18 years, 25 mg at bedtime, increased if necessary after 2 weeks to 50 mg at bedtime

nausea, vomiting, diarrhoea, constipation, abdominal pain, increased serum transaminases (see Hepatoxicity above), headache, dizziness, drowsiness, agitation, sleep disturbances, fatigue, anxiety, back pain, sweating; less commonlyparaesthesia, restless legs syndrome, blurred vision, tinnitus, eczema; rarely hepatitis, hepatic failure (see Hepatotoxicity above), weight changes, rash; suicidal behaviour (see Suicidal Behaviour and Antidepressant Therapy) and pruritus also reported